The 595 route has a high integration with the Cape Coral routes, picking up and dropping off with the 340 bus on North Del Prado, and doing the same with the 370 Southbound Bus at 2327 Hancock Bridge Parkway and the 340 Northbound Bus at Orange Grove and Pondella Rd. Of course, it meets every hour with the 590 Bus at Merchant's Crossing, as well as at Commerce Creek where passengers picked up by the 590 along Pine Island Rd. can be exchanged. Both the 595 and 590 Buses pick up at the VA Hospital where veterans there can have access to either an eastbound trip to North Fort Myers, southbound on the 140 Bus, or westward to Cape Coral.
The 595 Bus takes over the Waterway Estates area for the 370 Route, which picks up passengers to hand them off to the 370 Route at 2327 Hancock Bridge, where the 595 takes its ten-minute recovery stop. One of the neat things about the configuration of the 595 is that people who live off Pondella, in Tropic Isles and in Waterway Estates can have a westward trip to the Target at Pine Island Rd. because the buses in this area connect this way in a logical fashion. This trip is not possible with LeeTran's present service without taking hours to wait for a bus on North Del Prado or to walk the distance from Hancock Bridge to Pine Island Rd.
For its final trip, the 595 heads to Cape Coral Hospital where it meets with the 370N and 370S at 9:39pm to take any passengers over the Midpoint Bridge to end its day at the Edison Mall at 9:59pm.